My latest post on quora:
Lithium
Must Watch Video!
Abilify, Abilify Maintena, Acceptance, Activism, Allies, Anti-anxiety meds, Anti-depressants, Anti-psychotics, Anxiety, Anxiety Attacks, awareness, Bipolar, BPD, Brain, Depakote, Depression, Diseases, DSM-5, Effexor, Emergency Room, Families, Family, Geodon, Haldol, Health, Kristin Bell, learning through film, Lithium, Mania, Manic, Manic-Depressive, MAO Inhibitors, medical, Medicine, Mental Health, Mental Illness, Obsessive-Compulsive Disorder, ocd, Prozac, Psych Meds, Psychiatrist, Psychiatry, Psycho, Psychoactive Substances, psychoanalysis, Psychology, Psychosis, schizoaffective disorder, Schizophrenia, Seroquel, sickness, stigma, Stories, Suicide, Support System, Surviving, symptoms, TED Talk, treatment, treatment of the mentally ill, Video, Zoloft, ZyprexaThis is a great presentation/speech. I hope you can watch and share it! It really needs to go viral! Hopefully the correct video will play. It is a TED talk about mental illness and community.
Suicide
2013, Addiction, Alcohol, Alcoholics, Anorexia, Bipolar, Borderline Personality, BPD, Bulimia, Bullying, Compulsive Eating, Compulsive Exercising, Counselor, Dead, death, Depression, Dyke, end of world, Fag, Fat, Fat Hatred, Gay, GBLT, gender, Homo, Homophobia, Homosexual, Hope, insanity, Lesbian, Lithium, Lunatic, Mania, Manic, Manic-Depressive, Mental Health, Mental Illness, ocd, Panic Attacks, Pansexual, Paranoid Schizophrenia, Problems, Psych Meds, Psycho, Psychosis, Queer, Schizophrenia, self-care, Self-Harm, Self-Injury, Sleep Disorders, Suicide, Support System, Surviving, Trannie, Trans
You Know Your Symptoms the Best!
2013, Abilify, Abilify Maintena, Anti-anxiety meds, Anti-depressants, Anti-psychotics, Anxiety, Anxiety Attacks, Bipolar, Borderline Personality, BPD, Brain, Bulimia, Compulsive Eating, Compulsive Exercising, DBT, Depression, Eating Disorders, EDNOS, Education, Haldol, Haldol DEC, Haldol Decanoate, Happy, Health, Injections, Kristin Bell, Lithium, long-acting injectables, Mania, Manic, Manic-Depressive, Mental Health, Mental Illness, Mood Stabilizers, negative symptoms, Obsessive-Compulsive Disorder, ocd, Paranoid Schizophrenia, Prescription Meds, Psych Meds, Psychiatrist, Psychiatry, Psychiatry Denial, Psycho, Psychoactive Substances, psychoanalysis, Psychology, Psychosis, schizoaffective disorder, Schizophrenia, self-care, Self-Harm, Self-Injury, stigma, Stress, Support System, symptoms, treatment, Zoloft, Zyprexa
Recently I made a medication change (with the help of my psychiatrist), and as you might know from your own interactions with meds sometimes it can cause issues to develop. I was happily strolling along for a couple of months with a few bad days here and there, and then I started to notice the bad days piling up more often. I was really irritable, sad, became unmotivated, and suicide starting sounding better. I became alarmed, because I knew something was going wrong, but how was I supposed to explain to my psychiatrist that “irritable” is a symptom for me?
The problem with mental illness is that even when we fit into a diagnosed category of disorder, we all have our own unique symptoms that we need to pay attention to. I have schizophrenia, but for years I didn’t appear “sick enough” to most doctors, because they expected me to be talking to the walls and completely disheveled. There were times when I was talking to the walls and completely disheveled, but the doctors rarely saw me during those times, so they figured I wasn’t that bad off. Because I could communicate relatively well most doctors dismissed schizophrenia as a diagnosis.
Over the years I have come to realize what my symptoms are (for the most part), and now that I am doing better I can advocate for myself more effectively. However, it still isn’t easy to call up my psychiatrist and say “wow, I’m extremely irritable, this isn’t normal for me, and I need to increase my meds.” Most psychiatrists won’t believe that “irritable” is in any way related to schizophrenia, but for me (and many others) it is. I don’t become psychotic over night, and I don’t believe that I should have to be talking to walls in order to get the help I need. I also don’t believe that people should have to try to kill themselves before mental health professionals take people seriously.
Unfortunately, a lot of mental health professionals won’t take a person seriously unless they are debilitated to the point of needing to be hospitalized. So, as people living with mental illness or people who love people with mental illness, we have to be very proactive about getting the help we need before it turns into a crisis. Think about the good days and what you are like on those days, and compare them to the bad days. What are YOUR symptoms? How do things manifest in your day to day life? You might want to write down what you know your symptoms to be, and take that list with you when you talk to your doctor. It isn’t easy or fun, but we have to advocate for ourselves even when we are not doing our best.
In the end, you know your symptoms the best. Remember that you aren’t “crazy” for wanting to feel better and you aren’t making up excuses. Be pragmatic and straightforward, and get the help you need.
Schizophrenia and Negative Symptoms: Q&A with Dr. Potkin
2013, Abilify, affective flattening, alogia, Anti-anxiety meds, Anti-depressants, Anti-psychotics, asociality, avolition, Biology, Bipolar, Brain, Depakote, Depression, dopamine hypothesis, Dr. Steven G. Potkin, drugs, Education, Genentech, Geodon, Haldol, Haldol DEC, Haldol Decanoate, Health, insanity, Irvine (UCI), Kristin Bell, Lithium, Mania, Manic, Medicine, Mental Health, Mental Illness, Mood Stabilizers, N-methyl-D-aspartate, NAMI, negative symptoms, neuron, neuroscience, neurotransmitters, NMDA, NMDA receptor hypofunction hypothesis, Paranoid Schizophrenia, Paxil, Prescription Meds, Psych Meds, Psychiatrist, Psychiatry, Psychiatry Denial, Psycho, Psychoactive Substances, psychoanalysis, Psychology, Psychosis, Risperdal, schizoaffective disorder, Schizophrenia, Science, Seroquel, stigma, Support System, Surviving, symptoms, synapse, sz, Therapist, Trazadone, treatment, treatment-resistant, Trilifon, Wellbutrin, Zoloft, Zyprexa
I have some great news! I was able to ask Dr. Steven G. Potkin, Professor of Psychiatry in the Department of Psychiatry and Human Behavior at the University of California, Irvine (UCI) Medical Center, some questions regarding the negative symptoms of schizophrenia. He is also the Robert R. Sprague Endowed Chair in Brain Imaging. It was a brief, by email interview, but I’m happy to share what I’ve learned with you all! The following is the Q&A:
Kristin: What are negative symptoms?
Dr. Potkin: “Negative” does not refer to a person’s attitude, but instead to a lack of characteristics that should be present. Symptoms include reduced amount and content of speech, even when encouraged to interact (alogia), lack of emotional and facial expression (affective flattening), diminished ability to begin and sustain activities (avolition), decreased ability to find pleasure in everyday life (anhedonia) and social withdrawal (asociality). [1] [2]
Negative symptoms can appear a few years before other symptoms appear in young adulthood in the so-called “prodromal” stage of the illness.[3] Unfortunately these symptoms often go undetected because they manifest themselves as issues common among teenagers: social withdrawal, problems with school work, irritability, depression and sleeping problems.[4]
Kristin: Do all people with schizophrenia have negative symptoms?
Dr. Potkin: No, but at any point in time, negative symptoms can affect approximately 50 percent or more of people with schizophrenia.[5] [6]
Kristin: How do negative symptoms affect a person with schizophrenia? How do they affect their family and friends?
Dr. Potkin: Research suggests that for people living with schizophrenia, negative symptoms are key factors in poor quality of life as well as problems with personal hygiene, school and work performance, maintaining relationships, interacting within the community, and participating in social activities. [7] [8] [9] [10]
For caregivers of people with schizophrenia, negative symptoms may cause more burden than do other types of symptoms as they see their loved ones life isolated and lacking in meaning or joy. [11]
Kristin: How are negative symptoms currently treated?
Dr. Potkin: Current treatments for schizophrenia focus on reducing characteristic symptoms and can include both medication and psychosocial interventions.[12] No effective medication treatment has yet been approved for specific treatment of negative symptoms. Despite progress in the medication side of treatment, there are still unmet needs in terms of symptom control. A large study found that despite treatment, approximately 57 percent of people receiving treatment for a schizophrenia spectrum disorder still had at least one negative symptom.[10]
Kristin: What is the research that Genentech is doing regarding negative symptoms?
Dr. Potkin: Researchers at Genentech are pursuing new treatment strategies for schizophrenia, including increasing N-methyl-D-aspartate (NMDA) receptor activity in the brain in order to target the mechanism that may be a common link between the positive, negative and cognitive symptoms of the disorder.[7] [9] [11] [12]
Specifically, through a clinical trial program, Genentech is looking at an investigational medication for people with schizophrenia, including people who experience mostly negative symptoms of schizophrenia, despite taking medication. For more information, please visit www.SearchLyteschizophrenia.com
Kristin: How can family and friends of someone with schizophrenia help someone with negative symptoms?
Dr. Potkin: Caregivers can talk to doctors about interventions including medication, psychosocial rehabilitation (work, school, relationships), medical care and wellness, and therapy (e.g. cognitive behavioral therapy and peer support groups), as well as ongoing clinical trials.[13] They can work with physicians to find the medications and non-medicine therapies that are right for their loved one. Different medicines may have different side effects. Caregivers can also consider programs from the National Alliance on Mental Illness (NAMI) including:
• NAMI Hearts and Minds
– Online, interactive wellness initiative
• NAMI Peer-to-Peer
– Free, 9-week educational course on recovery
• NAMI Connection
– Recovery support group for adults
Kristin: Do scientists know the biological mechanisms involved in negative symptoms? If so, what are the areas of the brain and/or mechanisms involved in negative symptoms?
Dr. Potkin: In the 1970s, the “dopamine hypothesis” of schizophrenia emerged, suggesting the biological basis of schizophrenia was an excess of signaling by dopamine, a chemical messenger in the brain. This theory, however, could not explain negative or cognitive symptoms.[6] In the late 1980’s a newer theory suggested positive, negative and cognitive symptoms could all be due to reduced function of NMDA receptors in the brain. This theory is now known as the “NMDA receptor hypofunction hypothesis.”[6] [7] [8] [9]
Researchers are pursuing new treatment strategies for schizophrenia, including increasing NMDA receptor function in the brain in order to target the mechanism that may be a common link between the positive, negative and cognitive symptoms of the disorder.[7] [9] [11] [12] It is thought that NMDA receptor activity is an important pathway in psychiatric disorders, especially schizophrenia.
End of article.
*Note: I would like to thank Dr. Potkin for helping me put together this interview. This research is very exciting and I hope that negative symptoms can be tackled in this decade! I know how debilitating they can be!
______________________________
1. Gard DE, Kring AM, Gard MG, Horan WP, Green MF. Anhedonia in schizophrenia: distinctions between anticipatory and consummatory pleasure. Schizophr Res. Jul 2007;93(1-3):253-260.
2. Strauss GP, Gold JM. A new perspective on anhedonia in schizophrenia. Am J Psychiatry. Apr 2012;169(4):364-373.
3. Stahl SM. Stahl’s Essential Psychopharacology: Neuroscientific Basis and Practical Applications. 3rd ed. New York: Cambridge University Press; 2008.
4. National Institute of Mental Health. Schizophrenia. 2009; http://www.nimh.nih.gov/health/publications/schizophrenia/complete-index.shtml. Accessed July 7, 2012.
5. Kirkpatrick B, Fenton WS, Carpenter WT, Jr., Marder SR. The NIMH-MATRICS consensus statement on negative symptoms. Schizophr Bull. Apr 2006;32(2):214-219.
6. Bobes J, Arango C, Garcia-Garcia M, Rejas J. Prevalence of negative symptoms in outpatients with schizophrenia spectrum disorders treated with antipsychotics in routine clinical practice: findings from the CLAMORS study. J Clin Psychiatry. Mar 2010;71(3):280-286.
7. Ho BC, Nopoulos P, Flaum M, Arndt S, Andreasen NC. Two-year outcome in first-episode schizophrenia: predictive value of symptoms for quality of life. Am J Psychiatry. Sep 1998;155(9):1196-1201.
8. Kirkpatrick B, Fenton WS, Carpenter WT, Jr., Marder SR. The NIMH-MATRICS consensus statement on negative symptoms. Schizophr Bull. Apr 2006;32(2):214-219.
9. Kurtz MM. Symptoms versus neurocognitive skills as correlates of everyday functioning in severe mental illness. Expert Rev Neurother. Jan 2006;6(1):47-56.
10. Milev P, Ho BC, Arndt S, Andreasen NC. Predictive values of neurocognition and negative symptoms on functional outcome in schizophrenia: a longitudinal first-episode study with 7-year follow-up. Am J Psychiatry. Mar 2005;162(3):495-506.
11. Provencher HL, Mueser KT. Positive and negative symptom behaviors and caregiver burden in the relatives of persons with schizophrenia. Schizophr Res. Jul 25 1997;26(1):71-80.
12. National Institute of Mental Health. Schizophrenia. 2009; http://www.nimh.nih.gov/health/publications/schizophrenia/complete-index.shtml. Accessed July 7, 2012.
13. National Institute of Mental Health. Schizophrenia. 2009; http://www.nimh.nih.gov/health/publications/schizophrenia/complete-index.shtml. Accessed July 7, 2012.
Genetic Testing! Yay!
Abilify, Anti-anxiety meds, Anti-depressants, Anti-psychotics, Anxiety, benadryl, Biology, Bipolar, Body, BPD, Buspar, Depakote, Depression, dna, drugs, Effexor, genetic testing, Genetics, Haldol, Haldol DEC, Haldol Decanoate, Kristin Bell, Lithium, Mania, Manic, Manic-Depressive, MAO Inhibitors, Medicine, Mental Health, Mental Illness, metabolic pathways, metabolize, Mood Stabilizers, Navane, neuroscience, Obsessive-Compulsive Disorder, ocd, Paranoid Schizophrenia, Paxil, plavix, Prescription Meds, Prozac, Psych Meds, Psychiatrist, Psychiatry, Psychoactive Substances, Psychology, Psychosis, Risperdal, schizoaffective disorder, Schizophrenia, Science, Seroquel, Technology, testing, Trazadone, Trilifon, warfarin, Wellbutrin, Zoloft, Zyprexa
Hey Everybody! I wanted to share with you this cool genetics testing that is available to people. I just got it done, because my nurse practitioner ordered it and Medicare pays for it. (Medicare pays for this testing, because it saves a LOT of money and can save lives!) It is really cool, because it tells you how medications will interact with your specific genetic makeup! It is extremely important if you are taking really any kind of medication. For example, had I known about my results before I took Wellbutrin years ago, it would have saved me from basically having a manic reaction to the medication. It turns out that I metabolize differently than normal on some of the metabolic pathways. This means that I will metabolize the meds on those pathways different than people without this issue. If you have Medicare, I strongly urge you to get this testing done. It could save your life from a bad genetic-medication mistake. I think many other insurance carriers might also pay for it. It also explains why I can take a lower dose of many medications and still get the desired effect from the medication. I would say that anyone who is trying to figure out their psych meds should really get this testing done too. It doesn’t just tell about psych meds though, it tells about stuff involving all other sorts of meds. Seriously, this is pretty awesome! Again, here is the link: http://www.genemedrx.com/
Review: Loud In the House of Myself by Stacy Pershall
Acceptance, Anorexia, Anti-anxiety meds, Anti-depressants, Anti-psychotics, Anxiety, Ativan, Autobiography, Binge Eating, Bipolar, Black & White, Body, Body Image, Books, Borderline Personality, Bulimia, Compulsive Eating, Compulsive Exercising, Depakote, Depression, Eating Disorders, EDNOS, insanity, Internet, Kristin Bell, Lithium, Loud In the House of Myself, Mania, Manic, Manic-Depressive, MAO Inhibitors, memoir, Mental Health, Mental Illness, Mood Stabilizers, Navane, Prozac, Psych Meds, Psychiatrist, Psychiatry, Psychoactive Substances, Psychology, Reading, Review, Self-Harm, Self-Injury, Stacy Pershall, Stories, strange girl, Suicide, Surviving, Thin, Weightloss
Loud In the House of Myself: Memoir of a Strange Girl is a new book by Stacy Pershall. Of course, I was immediately drawn to this memoir, because it is a) a memoir b) about a “strange girl” and c) deals with mental illness. Yay! Since I’m undoubtably a strange mentally ill girl, I knew I had to read this. Pershall writes about her life growing up in Arkansas and her morphing from an über-sensitive child into a teenager and young adult with Borderline and Bipolar issues. Anyone familiar with the mental illness memoir genre will certainly have heard of Elizabeth Wurtzel, and I just bring her up, because UNLIKE Wurtzel, Pershall is not whiny in her writing! Pershall is matter-of-fact about her trials and symptoms, even though the reader can imagine the actual playing out of illness to be much more harsh and unbearable.
Pershall describes her unrelenting eating disorder, mood swings and suicide attempts with a steady and precise hand. This book seems really accessible to me, because Pershall speaks not only to those of us who have been through the mental health care system, but also to people who might not really understand this special weirdness. The only thing I would like to see more of in this book is more OF this book! haha. Seriously though, I enjoyed reading this memoir and would love to read more from Pershall. I would especially recommend this book to people struggling with Borderline Personality Disorder. There is a special misery only known by Borderlines that is never really represented in the books that ostensibly deal with Borderline Personality Disorder. I really wish there were more accounts like this that show the uncrazy through the crazy of Borderline Personality Disorder.
I Feel For Ya, Britney!
Anti-anxiety meds, Anti-depressants, Anti-psychotics, Bipolar, Britney Spears, Bulimia, Buspar, Drama, Kristin Bell, Lithium, Mania, Manic, Manic-Depressive, Medicine, Mental Health, Mental Illness, Mood Stabilizers, Prescription Meds, Problems, Psych Meds, Psychiatrist, Psychiatry, Psychiatry Denial, Psycho, Psychosis, Schizophrenia, Support System, Surviving, Therapist
Okay, I rarely write about celebrity gossip, but overnight Britney Spears was taken into the hospital for psychiatric evaluation and I guess I feel the need to comment. From what I’ve heard on the news, she hasn’t slept since Saturday and she’s now on a 72-hour hold. I have also been
Tips And Tricks For Surviving A Mental Illness #11
Alcohol, Amblify, Anti-depressants, Anti-psychotics, Anxiety, Buspar, Depakote, Depression, Drama, Family, Friends, Haldol DEC, Health, Holidays, Kristin Bell, Lithium, Lunatic, Mental Health, Mental Illness, Mood Stabilizers, Panic Attacks, Paxil, Prozac, Psych Meds, Psychiatrist, Psychiatry, Psychiatry Denial, Psycho, Psychosis, Relaxation, Risperdal, Schizophrenia, Seroquel, Sleep Disorders, Support System, Surviving, Tips & Tricks, Wellbutrin, Xanex, Zoloft, Zyprexa
Whew! It has been awhile since I have written a tip/trick. The last few months have been crazy, but not really in a good way. Oh well. The tip I’m writing about today has to do with this special time of year for people. This may be rather specific to people who are in the US and/or to people who celebrate certain holidays. Anyway, in the US most people have some holiday that they celebrate or they go on vacation or just have some time off. The major holidays are Thanksgiving, Chanukah, Kwanza, Christmas, New Year’s Eve and New Year’s Day. Again, I know there are more holidays that I’m sure I’m missing, but these are the big ones. So, here is my tip:
Tips And Tricks For Surviving A Mental Illness #10
Acceptance, Amblify, Anti-anxiety meds, Anti-depressants, Anti-psychotics, Anxiety, Anxiety Attacks, Ativan, benadryl, Bipolar, Body, Buspar, Delayed Sleep Phase Disorder, Depakote, Depression, Effexor, Geodon, Haldol, Kristin Bell, Lithium, Maintenance, MAO Inhibitors, Medicine, melatonin, Mental Health, Mental Illness, Mood Stabilizers, Panic Attacks, Paxil, Pot, Prescription Meds, Problems, Prozac, Psych Meds, Psychiatrist, Psychiatry, Psychiatry Denial, Psycho, Psychosis, Relaxation, Risperdal, Schizophrenia, Seroquel, Sleep, Sleep Disorders, Surviving, Tips & Tricks, Trazadone, Trilifon, Wellbutrin, Xanex, Zoloft, Zyprexa
<Sleeping graphic from HowStuffWorks.com>
I don’t know why I didn’t think of this tip before. Probably because I haven’t mastered this and should really follow my own advice about it. Plus my dad likes to harp on me about my problem with this a lot…which just irritates me. On with tip 10.
kristinbell.org 