Must Watch Video!

December 10, 2014 at 4:58 am | Posted in Abilify, Abilify Maintena, Acceptance, Activism, Allies, Anti-anxiety meds, Anti-depressants, Anti-psychotics, Anxiety, Anxiety Attacks, awareness, Bipolar, BPD, Brain, Depakote, Depression, Diseases, DSM-5, Effexor, Emergency Room, Families, Family, Geodon, Haldol, Health, Kristin Bell, learning through film, Lithium, Mania, Manic, Manic-Depressive, MAO Inhibitors, medical, Medicine, Mental Health, Mental Illness, Obsessive-Compulsive Disorder, ocd, Prozac, Psych Meds, Psychiatrist, Psychiatry, Psycho, Psychoactive Substances, psychoanalysis, Psychology, Psychosis, schizoaffective disorder, Schizophrenia, Seroquel, sickness, stigma, Stories, Suicide, Support System, Surviving, symptoms, TED Talk, treatment, treatment of the mentally ill, Video, Zoloft, Zyprexa | Leave a comment

This is a great presentation/speech. I hope you can watch and share it! It really needs to go viral! Hopefully the correct video will play. It is a TED talk about mental illness and community.

Schizophrenia and Negative Symptoms: Q&A with Dr. Potkin

May 20, 2013 at 7:48 pm | Posted in 2013, Abilify, affective flattening, alogia, Anti-anxiety meds, Anti-depressants, Anti-psychotics, asociality, avolition, Biology, Bipolar, Brain, Depakote, Depression, dopamine hypothesis, Dr. Steven G. Potkin, drugs, Education, Genentech, Geodon, Haldol, Haldol DEC, Haldol Decanoate, Health, insanity, Irvine (UCI), Kristin Bell, Lithium, Mania, Manic, Medicine, Mental Health, Mental Illness, Mood Stabilizers, N-methyl-D-aspartate, NAMI, negative symptoms, neuron, neuroscience, neurotransmitters, NMDA, NMDA receptor hypofunction hypothesis, Paranoid Schizophrenia, Paxil, Prescription Meds, Psych Meds, Psychiatrist, Psychiatry, Psychiatry Denial, Psycho, Psychoactive Substances, psychoanalysis, Psychology, Psychosis, Risperdal, schizoaffective disorder, Schizophrenia, Science, Seroquel, stigma, Support System, Surviving, symptoms, synapse, sz, Therapist, Trazadone, treatment, treatment-resistant, Trilifon, Wellbutrin, Zoloft, Zyprexa | Leave a comment

negsymp I have some great news! I was able to ask Dr. Steven G. Potkin, Professor of Psychiatry in the Department of Psychiatry and Human Behavior at the University of California, Irvine (UCI) Medical Center, some questions regarding the negative symptoms of schizophrenia. He is also the Robert R. Sprague Endowed Chair in Brain Imaging. It was a brief, by email interview, but I’m happy to share what I’ve learned with you all! The following is the Q&A:

Kristin: What are negative symptoms?
Dr. Potkin: “Negative” does not refer to a person’s attitude, but instead to a lack of characteristics that should be present. Symptoms include reduced amount and content of speech, even when encouraged to interact (alogia), lack of emotional and facial expression (affective flattening), diminished ability to begin and sustain activities (avolition), decreased ability to find pleasure in everyday life (anhedonia) and social withdrawal (asociality). [1] [2]

Negative symptoms can appear a few years before other symptoms appear in young adulthood in the so-called “prodromal” stage of the illness.[3] Unfortunately these symptoms often go undetected because they manifest themselves as issues common among teenagers: social withdrawal, problems with school work, irritability, depression and sleeping problems.[4]

Kristin: Do all people with schizophrenia have negative symptoms?
Dr. Potkin: No, but at any point in time, negative symptoms can affect approximately 50 percent or more of people with schizophrenia.[5] [6]

Kristin: How do negative symptoms affect a person with schizophrenia? How do they affect their family and friends?
Dr. Potkin: Research suggests that for people living with schizophrenia, negative symptoms are key factors in poor quality of life as well as problems with personal hygiene, school and work performance, maintaining relationships, interacting within the community, and participating in social activities. [7] [8] [9] [10]

For caregivers of people with schizophrenia, negative symptoms may cause more burden than do other types of symptoms as they see their loved ones life isolated and lacking in meaning or joy. [11]

Kristin: How are negative symptoms currently treated?
Dr. Potkin: Current treatments for schizophrenia focus on reducing characteristic symptoms and can include both medication and psychosocial interventions.[12] No effective medication treatment has yet been approved for specific treatment of negative symptoms. Despite progress in the medication side of treatment, there are still unmet needs in terms of symptom control. A large study found that despite treatment, approximately 57 percent of people receiving treatment for a schizophrenia spectrum disorder still had at least one negative symptom.[10]

Kristin: What is the research that Genentech is doing regarding negative symptoms?
Dr. Potkin: Researchers at Genentech are pursuing new treatment strategies for schizophrenia, including increasing N-methyl-D-aspartate (NMDA) receptor activity in the brain in order to target the mechanism that may be a common link between the positive, negative and cognitive symptoms of the disorder.[7] [9] [11] [12]

Specifically, through a clinical trial program, Genentech is looking at an investigational medication for people with schizophrenia, including people who experience mostly negative symptoms of schizophrenia, despite taking medication. For more information, please visit www.SearchLyteschizophrenia.com

Kristin: How can family and friends of someone with schizophrenia help someone with negative symptoms?
Dr. Potkin: Caregivers can talk to doctors about interventions including medication, psychosocial rehabilitation (work, school, relationships), medical care and wellness, and therapy (e.g. cognitive behavioral therapy and peer support groups), as well as ongoing clinical trials.[13] They can work with physicians to find the medications and non-medicine therapies that are right for their loved one. Different medicines may have different side effects. Caregivers can also consider programs from the National Alliance on Mental Illness (NAMI) including:

• NAMI Hearts and Minds

– Online, interactive wellness initiative

www.nami.org/heartsandminds

• NAMI Peer-to-Peer

– Free, 9-week educational course on recovery

www.nami.org/peertopeer

• NAMI Connection

– Recovery support group for adults

www.nami.org/connection

Kristin: Do scientists know the biological mechanisms involved in negative symptoms? If so, what are the areas of the brain and/or mechanisms involved in negative symptoms?
Dr. Potkin: In the 1970s, the “dopamine hypothesis” of schizophrenia emerged, suggesting the biological basis of schizophrenia was an excess of signaling by dopamine, a chemical messenger in the brain. This theory, however, could not explain negative or cognitive symptoms.[6] In the late 1980’s a newer theory suggested positive, negative and cognitive symptoms could all be due to reduced function of NMDA receptors in the brain. This theory is now known as the “NMDA receptor hypofunction hypothesis.”[6] [7] [8] [9]

Researchers are pursuing new treatment strategies for schizophrenia, including increasing NMDA receptor function in the brain in order to target the mechanism that may be a common link between the positive, negative and cognitive symptoms of the disorder.[7] [9] [11] [12] It is thought that NMDA receptor activity is an important pathway in psychiatric disorders, especially schizophrenia.

End of article.

*Note: I would like to thank Dr. Potkin for helping me put together this interview. This research is very exciting and I hope that negative symptoms can be tackled in this decade! I know how debilitating they can be!

______________________________

1.     Gard DE, Kring AM, Gard MG, Horan WP, Green MF. Anhedonia in schizophrenia: distinctions between anticipatory and consummatory pleasure. Schizophr Res. Jul 2007;93(1-3):253-260.

2.     Strauss GP, Gold JM. A new perspective on anhedonia in schizophrenia. Am J Psychiatry. Apr 2012;169(4):364-373.

3.     Stahl SM. Stahl’s Essential Psychopharacology: Neuroscientific Basis and Practical Applications. 3rd ed. New York: Cambridge University Press; 2008.

4.     National Institute of Mental Health. Schizophrenia. 2009; http://www.nimh.nih.gov/health/publications/schizophrenia/complete-index.shtml. Accessed July 7, 2012.

5.     Kirkpatrick B, Fenton WS, Carpenter WT, Jr., Marder SR. The NIMH-MATRICS consensus statement on negative symptoms. Schizophr Bull. Apr 2006;32(2):214-219.

6.     Bobes J, Arango C, Garcia-Garcia M, Rejas J. Prevalence of negative symptoms in outpatients with schizophrenia spectrum disorders treated with antipsychotics in routine clinical practice: findings from the CLAMORS study. J Clin Psychiatry. Mar 2010;71(3):280-286.

7.     Ho BC, Nopoulos P, Flaum M, Arndt S, Andreasen NC. Two-year outcome in first-episode schizophrenia: predictive value of symptoms for quality of life. Am J Psychiatry. Sep 1998;155(9):1196-1201.

8.     Kirkpatrick B, Fenton WS, Carpenter WT, Jr., Marder SR. The NIMH-MATRICS consensus statement on negative symptoms. Schizophr Bull. Apr 2006;32(2):214-219.

9.     Kurtz MM. Symptoms versus neurocognitive skills as correlates of everyday functioning in severe mental illness. Expert Rev Neurother. Jan 2006;6(1):47-56.

10.   Milev P, Ho BC, Arndt S, Andreasen NC. Predictive values of neurocognition and negative symptoms on functional outcome in schizophrenia: a longitudinal first-episode study with 7-year follow-up. Am J Psychiatry. Mar 2005;162(3):495-506.

11.   Provencher HL, Mueser KT. Positive and negative symptom behaviors and caregiver burden in the relatives of persons with schizophrenia. Schizophr Res. Jul 25 1997;26(1):71-80.

12.   National Institute of Mental Health. Schizophrenia. 2009; http://www.nimh.nih.gov/health/publications/schizophrenia/complete-index.shtml. Accessed July 7, 2012.

13.   National Institute of Mental Health. Schizophrenia. 2009; http://www.nimh.nih.gov/health/publications/schizophrenia/complete-index.shtml. Accessed July 7, 2012.

NIMH Schizophrenia Research Participation

February 4, 2008 at 6:39 am | Posted in Amblify, Anti-psychotics, Ativan, Bipolar, Family, Geodon, Haldol, Haldol DEC, Haldol Decanoate, Health, Kristin Bell, Lunatic, Mental Health, Mental Illness, Navane, Paxil, Prescription Meds, Psych Meds, Psychiatrist, Psychiatry, Psychiatry Denial, Psycho, Psychosis, Research, Risperdal, Schizophrenia, Seattle, Surviving, Trazadone, Trilifon, US Government, Zyprexa | 2 Comments
labratme

Oh, so I haven’t blogged about this yet, but I went up to Seattle with my family about a week ago and participated in the National Institute of Mental Health-funded research project regarding schizophrenia. I had a really great time and the research team was totally fabulous and wonderful!

So, we arrived on a Wednesday afternoon. They took blood samples from Continue Reading NIMH Schizophrenia Research Participation…

A Book Everyone Should Read!

December 24, 2007 at 3:06 pm | Posted in Acceptance, Activism, Anti-anxiety meds, Anti-depressants, Anti-psychotics, Bipolar, Books, Counselor, Discrimination, Elyn R. Saks, Geodon, Haldol, Haldol DEC, Haldol Decanoate, Kristin Bell, Lunatic, Medicine, Mental Health, Mental Illness, Navane, NIMH, Prescription Meds, Problems, Psych Meds, Psychiatrist, Psychiatry, Psychiatry Denial, Psycho, Psychosis, Reading, Risperdal, Schizophrenia, Seroquel, Surviving, The Center Cannot Hold, Therapist, Trazadone, Trilifon | Leave a comment
saksbook

I just finished reading Elyn R. Saks’ book, The Center Cannot Hold, and I highly recommend it to everyone, especially people who are touched by someone who has mental illness. The book is a memoir of Ms. Saks’ life and coming to terms with schizophrenia. From an early age she recalls having strange thoughts, but Continue Reading A Book Everyone Should Read!…

Schizophrenia Research I’m Participating In

December 2, 2007 at 6:32 pm | Posted in Acceptance, Amblify, Anti-anxiety meds, Anti-depressants, Anti-psychotics, Anxiety, Family, Fun, Geodon, Haldol, Haldol DEC, Haldol Decanoate, Kristin Bell, Lunatic, Measurements, Medicine, Mental Health, Mental Illness, Mood Stabilizers, NIMH, Prescription Meds, Problems, Psych Meds, Psychiatrist, Psychiatry, Psychiatry Denial, Psycho, Psychosis, Research, Risperdal, Schizophrenia, Support System, Surviving, Therapist, Tips & Tricks, Trazadone, Trilifon, Zoloft, Zyprexa | 4 Comments

eye tracking

You might be asked to participate in an eye tracking exercise like the one shown above. All of the equipment is just used to keep your head still and to track your eyes.

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I just wanted to let you all know about this schizophrenia research study I am most likely going to be participating in and I hope that if any of you out there are interested, you will join in on the study! Well, as you might know, I got a new job at schizophrenia.com. Well, one day I was visiting the site and an ad popped up looking for research participants for this schizophrenia research study! Here is the link: http://www.schizophreniaresearch.net/Involved.asp

Unfortunately, at this time it isn’t an Continue Reading Schizophrenia Research I’m Participating In…

Tips And Tricks For Surviving A Mental Illness #10

October 17, 2007 at 6:38 am | Posted in Acceptance, Amblify, Anti-anxiety meds, Anti-depressants, Anti-psychotics, Anxiety, Anxiety Attacks, Ativan, benadryl, Bipolar, Body, Buspar, Delayed Sleep Phase Disorder, Depakote, Depression, Effexor, Geodon, Haldol, Kristin Bell, Lithium, Maintenance, MAO Inhibitors, Medicine, melatonin, Mental Health, Mental Illness, Mood Stabilizers, Panic Attacks, Paxil, Pot, Prescription Meds, Problems, Prozac, Psych Meds, Psychiatrist, Psychiatry, Psychiatry Denial, Psycho, Psychosis, Relaxation, Risperdal, Schizophrenia, Seroquel, Sleep, Sleep Disorders, Surviving, Tips & Tricks, Trazadone, Trilifon, Wellbutrin, Xanex, Zoloft, Zyprexa | 1 Comment

sleep

<Sleeping graphic from HowStuffWorks.com>

I don’t know why I didn’t think of this tip before. Probably because I haven’t mastered this and should really follow my own advice about it. Plus my dad likes to harp on me about my problem with this a lot…which just irritates me. On with tip 10. Continue Reading Tips And Tricks For Surviving A Mental Illness #10…

Common Fallacies of Psychiatry Deniers

September 20, 2007 at 8:53 pm | Posted in Acceptance, Amblify, Anti-depressants, Anti-psychotics, Bipolar, Buspar, Denial, Depakote, Depression, drugs, Education, Geodon, Haldol, Haldol DEC, Health, Kristin Bell, Lithium, Lunatic, MAO Inhibitors, Medicine, Mental Health, Mental Illness, Mood Stabilizers, Paxil, Prescription Meds, Psych Meds, Psychiatrist, Psychiatry, Psychiatry Denial, Psycho, Psychosis, Schizophrenia, Scientology, Seroquel, Shame, Support System, Surviving, Trazadone, Trilifon, Video, Wellbutrin, Zoloft, Zyprexa | 12 Comments

rob

The following videos are by Rob aka deidzoeb, a person from YouTube. His wife, Melinda, aka melsbasketcase, is also a YouTuber and Melinda has schizophrenia. She does well when she is properly medicated, but a lot of people go on her channel and try to convince her that her drugs are poison and that she should stop taking them. I hope you will watch all three of Rob’s great videos about Psychiatry Denial. He does a great job of showing how psychiatry deniers are simply wrong and how they try to take choice away from people with serious mental illnesses. I have included all three videos here. Please click to find them. Continue Reading Common Fallacies of Psychiatry Deniers…

Tips And Tricks For Surviving A Mental Illness #7

August 17, 2007 at 2:09 am | Posted in Acceptance, Amblify, Anti-depressants, Anti-psychotics, Bipolar, Buspar, Counselor, Denial, Depakote, Depression, Discrimination, drugs, Effexor, Geodon, Haldol, Health, Kristin Bell, Lithium, Lunatic, MAO Inhibitors, Medicine, Mental Health, Mental Illness, Mood Stabilizers, Navane, Paxil, Prescription Meds, Problems, Psych Meds, Psychiatrist, Psychiatry, Psycho, Psychosis, Risperdal, Schizophrenia, Scientology, Seroquel, Surviving, Thrive, Tips & Tricks, Trazadone, Trilifon, Wellbutrin, Zoloft, Zyprexa | 9 Comments

limbic

I don’t know if I am just stating the obvious with all of these Tips & Tricks, but sometimes it is the most obvious things that we forget when illness hits. This next tip is something that I have personally struggled with for years and sometimes a glimmer of it still pops up every now and then. Continue Reading Tips And Tricks For Surviving A Mental Illness #7…

Tips And Tricks For Surviving A Mental Illness #5

August 1, 2007 at 10:44 pm | Posted in AA, Acid, Alcohol, Alcoholics, Amblify, Anonymous, Anti-depressants, Anti-psychotics, Bipolar, Bong, Booze, Buspar, Cocaine, Coke, Counselor, Depakote, Depression, Downers, drugs, Ecstacy, Family, Friends, Geodon, Haldol, Haldol DEC, Haldol Decanoate, Health, Heroin, Kristin Bell, Life, Lithium, LSD, MAO Inhibitors, Marijuana, Mary Jane, Mental Health, Mental Illness, Mood Stabilizers, NA, Narcotics, Navane, Paxil, Pot, Prescription Meds, Problems, Prozac, Psych Meds, Psychiatrist, Psychiatry, Psycho, Psychosis, Risperdal, Schizophrenia, Seroquel, Smack, Social Worker, Teetotaller, Therapist, Tips & Tricks, Trazadone, Trilifon, Uppers, Weed, Wellbutrin, Zoloft, Zyprexa | 2 Comments

brainscan

Okay, I know I’m in trouble with this tip. I know there are some of you out there who are NOT going to like this one at all! Still I have to say it, because it is an issue. Continue Reading Tips And Tricks For Surviving A Mental Illness #5…

Tips And Tricks For Surviving A Mental Illness #4

July 31, 2007 at 2:43 am | Posted in Allies, Amblify, Anti-depressants, Anti-psychotics, Bipolar, Buspar, Counselor, Depakote, Depression, Discrimination, Effexor, Family, Friends, Geodon, Haldol, Haldol DEC, Haldol Decanoate, Kristin Bell, Lithium, MAO Inhibitors, Medicine, Mental Health, Mental Illness, Mood Stabilizers, Navane, Paxil, People, Problems, Prozac, Psych Meds, Psychiatrist, Psychiatry, Psycho, Psychosis, Risperdal, Schizophrenia, Seroquel, Shame, Social Worker, Support System, Surviving, Therapist, Tips & Tricks, Trazadone, Trilifon, Wellbutrin, Zoloft, Zyprexa | Leave a comment

braindiagram

I guess I sort of tipped you off to what I was going to be talking about in tip number three. Well, this next tip cannot be underestimated. It is really important no matter who you are, but for people with mental illness it is extremely important. Continue Reading Tips And Tricks For Surviving A Mental Illness #4…

Tips And Tricks For Surviving A Mental Illness #3

July 26, 2007 at 7:37 pm | Posted in Amblify, Anti-depressants, Anti-psychotics, Bipolar, Buspar, Depakote, Depression, Effexor, Geodon, Haldol, Haldol DEC, Haldol Decanoate, Health, Injections, Kristin Bell, Life, Lithium, MAO Inhibitors, Medicine, Mental Health, Mental Illness, Mood Stabilizers, Navane, Obsessions, Paxil, Problems, Prozac, Psych Meds, Psychiatrist, Psychiatry, Psycho, Psychosis, Relaxation, Risperdal, Schizophrenia, Seroquel, Stress, Surviving, Tips & Tricks, Trazadone, Trilifon, Wellbutrin, Zoloft, Zyprexa | 1 Comment

brainstress

Oh, just so you know, these tips aren’t in any particular order, except I did mean to put the first one first. Other than that they are sort of random. On with tip number three: Continue Reading Tips And Tricks For Surviving A Mental Illness #3…

Tips and Tricks For Surviving A Mental Illness #2

July 26, 2007 at 5:58 am | Posted in Amblify, Anti-depressants, Anti-psychotics, Bipolar, Buspar, Depakote, Depression, Effexor, Geodon, Haldol, Haldol DEC, Haldol Decanoate, Health, Injections, Kristin Bell, Lithium, MAO Inhibitors, Medicine, Mental Health, Mental Illness, Mood Stabilizers, Navane, Paxil, Problems, Prozac, Psych Meds, Psychiatry, Psycho, Psychosis, Risperdal, Schizophrenia, Seroquel, Surviving, Tips & Tricks, Trazadone, Trilifon, Wellbutrin, Zoloft, Zyprexa | 3 Comments

brain2

Okay, I know these tips and tricks might not be the most popular tips and tricks with everyone, but they are MY tips and tricks and how I have survived having a mental illness so far. Things could change at any minute. On with number two. Continue Reading Tips and Tricks For Surviving A Mental Illness #2…

Tips And Tricks For Surviving A Mental Illness #1

July 25, 2007 at 1:24 am | Posted in Amblify, Anti-depressants, Anti-psychotics, Bipolar, Buspar, Depakote, Depression, Effexor, Geodon, Haldol, Haldol DEC, Haldol Decanoate, Health, Injections, Kristin Bell, Lithium, MAO Inhibitors, Medicine, Mental Health, Mental Illness, Mood Stabilizers, Navane, Paxil, Problems, Prozac, Psych Meds, Psychiatry, Psycho, Psychosis, Risperdal, Schizophrenia, Seroquel, Shame, Surviving, Tips & Tricks, Trazadone, Trilifon, Wellbutrin, Zoloft, Zyprexa | 7 Comments

brain

Well, I think I know a thing or two about having a mental illness, since I’ve been dealing with this damn stuff since I was 15-years-old. So, why not share a few tips and tricks I’ve learned along the way? I guess I’ll just put up these when I have time. Here is the number one thing I’ve learned: Continue Reading Tips And Tricks For Surviving A Mental Illness #1…

The Haldol Injections

July 23, 2007 at 1:26 am | Posted in Bipolar, Buspar, Depression, Geodon, Haldol, Haldol DEC, Haldol Decanoate, Injections, Kristin Bell, Mental Health, Mental Illness, Psych Meds, Psychiatry, Psychosis, Schizophrenia, Zoloft | 15 Comments

haldol decanoate

I wanted to talk a little bit about the Haldol injections that I get. I have schizophrenia and part of the medications that I receive are Haldol injections. The long name is Haldol Decanoate or Haldol DEC for short. Continue Reading The Haldol Injections…

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